New results acquired in south-Brittany (MD08-3204 CQ core: Bay of Quiberon and VK03-58bis core: south Glénan islands) allow depicting Holocene paleoenvironmental changes from 8.5 ka BP to present through a multi-proxy dataset including sedimentological and palynological data. First, grain-size analyses and AMS-¹⁴C dates highlight a common sedimentary history for both study cores. The relative sea level (RSL) slowdown was accompanied by a significant drop of the sedimentation rates between ca. 8.3 and 5.7 ka BP, after being relatively higher at the onset of the Holocene. This interval led to the establishment of a shell-condensed level, identified in core VK03-58bis by the “Turritella layer” and interpreted as a marker for the maximum flooding surface. Palynological data (pollen grains and dinoflagellate cyst assemblages) acquired in core MD08-3204 CQ argue for an amplification of the fluvial influence since 5.7 ka BP; the establishment of the highstand system tract (i.e., mixed marine and fluviatile influences on the platform) then accompanying the slowdown of the RSL rise-rates. On the shelf, the amplification of Anthropogenic Pollen Indicators (API) is then better detected since 4.2 ka BP, not only due to human impact increase but also due to a stronger fluvial influence on the shelf during the Late Holocene. Palynological data, recorded on the 8.5–8.3 ka BP interval along an inshore-offshore gradient, also demonstrate the complexity of the palynological signal such as i) the fluvial influence that promotes some pollinic taxa (i.e., Corylus, Alnus) from proximal areas and ii) the macro-regionalization of palynomorph sources in distal cores. In addition, the comparison of palynological tracers, including API, over the last 7 kyrs, with south-Brittany coastal and mid-shelf sites subjected to northern vs. southern Loire catchment areas, allowed discussing a major hydro-climatic effect on the reconstructed palynological signals. Strengthened subpolar gyre dynamics (SPG), combined with recurrent positive North Atlantic Oscillation (NAO) configurations, appear responsible for increased winter precipitations and fluvial discharges over northern Europe, such as in Brittany. Conversely, weakened SPG intervals, associated with negative NAO-like modes, are characterized by intensified winter fluvial discharges over southern Europe. Interestingly, we record, at an infra-orbital timescale, major peaks of API during periods of strengthened (/weakened) SPG dynamics in sites subjects to Brittany watersheds (/Loire watersheds) inputs.