Combined use of optical (satellite imagery), and acoustic (sidescan sonar) remote sensing techniques, as well as in situ methodologies (visual census; SCUBA diving, Towed Underwater Cameras, and Remotely Operated Vehicles) was employed to map the spatial distribution of seagrass habitats in the coastal waters of the Hellenic territory. Seagrass meadows were recorded at approximately 70% of the Hellenic coastline (Eastern Ionian, Aegean and Levantine Seas), and their surface area exceeded 2,673.1 km2. Posidonia oceanica is -by far- the dominant seagrass species of the Hellenic seas, covering the vast majority of seabed at depths between the shoreline and 25 – 30 m (or deeper in insular areas), followed by the species Cymodocea nodosa, Zostera noltei, and Halophila stipulacea, which, however, presenting local presence and limited areal extent. Habitat suitability in terms of the seabed spatial extent that is available for the growth of seagrass meadows (i.e., the spatial extent of coastal areas between the shoreline and the isobath of 20m) and the seawater clarity conditions are highlighted as the critical factors for the formation of well-structured and extensive meadows. The results of this study are of great importance and usefulness for the effective management and conservation of valuable marine ecosystems.