Two quality controlled datasets here archived were collected during the oceanographic cruise BioArgoMed that held in Spring 2015 over the whole Mediterranean Sea, onboard R/V Tethys 2. The first datset is composed of continuous time series of sea surface temperature (TEMP in °C), sea surface salinity (practical scale, PSAL) and fluorescence of chlorophyll-a (FCHL in mg/m³) along the ship track, with a resolution of 5 minutes. The second dataset is composed of continuous time series of ocean currents profiles along the ship track with a resolution 1 km. The profiles are binned at 8m resolution from 18m until 570m. The quality controlled parameters are the depth (in m), the zonal current (UVEL in m/s) and the meridional current (VVEL in m/s).