This dataset contains 58 profiles of temperature, conductivity, salinity and turbulent dissipation in the upper ocean (0 - 50m) of a location in the open North Atlantic, off the North American coastal shelf (approximate location 40.27N, 58.9W). The profiles are obtained with the autonomous Air Sea Interaction Profiler (ASIP), which was deployed during a research cruise aboard the RV Knorr (USA) in June 2011. The dataset further contains meteorological observations made from the research vessel during this period. The outcome of the prognostic model by Bellenger et al. 2017, given an input of the combined oceanographic and meteorological observations to simulate seawater temperature and salinity at two depths near the surface, is also included. This dataset forms the basis of the JGR Oceans submission by ten Doeschate et al. 2019 "Upper Ocean Response to Rain Observed from a Vertical Profiler".