The present database collects data for artificial and natural reefs, and wrecks along the Adriatic Sea. Data has been collected from a large survey conducted through the ADRIREEF Interreg projects' partners, undergone a wide data harmonization in order to report answers to a consistent format, integrating survey data with literature data (scientific and grey), and data coming from different research projects. Parameters describing each natural, artificial reef and wreck are referable to four different groups: reef identification and geolocalisation information, summary of the characteristics of the area hosting the reef, aspects of the reefs that may also have an effect on the usage of the reef, present and/or possible future reef exploitation. In order to better visualize data, a webGIS has also been put in place and it is reachable at the address: https://adrireef.github.io/sandbox3/.The database counts 285 observations falling in Italian, Croatian and International waters. The database is available in a unique CSV file, where each element is described by 51 parameters, including coordinates in decimal degrees (WGS84 coordinate reference system) and bottom depth in meters, making data 3D. More information about data and single columns explanation is available in the attached README file.